Free PDF The Chemistry of Mind-Altering Drugs: History, Pharmacology, and Cultural Context (American Chemical Society Publication)
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The Chemistry of Mind-Altering Drugs: History, Pharmacology, and Cultural Context (American Chemical Society Publication)
Free PDF The Chemistry of Mind-Altering Drugs: History, Pharmacology, and Cultural Context (American Chemical Society Publication)
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Review
"An appropriate alternative title for this fascinating, modestly priced volume might be 'Everything You Always Wanted to Know about Drugs.' The author . . . has left no stone unturned in making this vade mecum of drugs, for specialist or layperson alike, as complete as possible . . . Clearly a labor of love. . . . I heartily recommend this interesting and informative study not only to chemists and pharmacologists but also to professionals, students and educators in the health sciences as well as to science-conscious citizens concerned with the social and ethical implications of the use of mind-altering drugs in our society." --George B. Kauffman in American Scientist"This book will provide a pleasant surprise for many readers! . . . I enthusiastically recommend it to anyone with basic science literacy who wants a good general overview of psychoactive substances, how they were discovered, and the roles they play in medicine and in our present culture." --David E. Nichols in Journal of Medicinal Chemistry"Mind-altering substances have captivated human beings through the ages and have certainly been in the forefront of local, national, and international politics for more than a century . . . Because this subject holds the interest of such a disparate group of individuals, it is not an easy task to write a book on this subject that would appeal to a diverse audience. Perrine has made a serious attempt to write such a book . . . Very readable and chocked with information . . . providing rich descriptions of the psychological and behavioral effects of mind-altering drugs." --Journal of the American Chemical Society
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From the Back Cover
This book, intended for a wide audience from college students and professors to organic, pharmaceutical, and medicinal chemists, provides an accessible explanation of drug-receptor interaction and organic chemical structures, as well as descriptions of the discovery, isolation, and syntheses of the chemical substances responsible for drug activity. It is a rigorous, scientifically objective, and thoroughly documented exposition of acute pharmacological and psychological effects of nearly every known substance that affects human consciousness, from alcohol to zopiclone. Also featured are first-hand accounts and descriptions of the social, cultural, and religious milieus in which many psychotropic plants are used.
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Product details
Series: American Chemical Society Publication
Paperback: 500 pages
Publisher: American Chemical Society; 1 edition (May 5, 1996)
Language: English
ISBN-10: 0841232539
ISBN-13: 978-0841232532
Product Dimensions:
9.9 x 1 x 6.8 inches
Shipping Weight: 1.8 pounds
Average Customer Review:
4.9 out of 5 stars
10 customer reviews
Amazon Best Sellers Rank:
#1,293,109 in Books (See Top 100 in Books)
Although this text is from 1996 it still is an absolute must have for anyone that works with Psychotropic Drugs or Patients that use or abuse them or that are prescribed them.Perrine gives an entertaining and elucidating account of the genesis of all the classes of mind altering drugs. Moreover, the book coherently explains the historical and cultural aspects surrounding the discovery and development of new drugs in each class of psychotropic compounds.Included, are some detailed accounts- sometimes tragic- of serendipitous yet monumental discoveries in psychopharmacology. A case in point is that of a graduate student intent on the clandestine chemical synthesis of a psychotropic compound. Inadvertently, he ended up with a contaminated product MPP+ which led to his untimely death and the death of others. Yet, this lab mishap ended up having profound implications for understanding the neurochemical mechanisms involved in Parkinson's Disease.A definite must have... I just wish an updated edition could be published!
I took Dr. Perrine's "Chemistry of Mind-Altering Drugs" undergraduate course at Loyola University and this is the classroom textbook! It is a discussion of the scientific, social, cultural, and religious implications of psychotropic drug activity. But a science background isn't required in order to understand or appreciate it.
Obligatory classic and unique on blend chemistry, pharmacology and social/historical context. Also deals the drug abuse in a clear and honest way and don't fall in the trap of the politicaly correct the plagues the drug abuse issue. It is sincere and still a good reference.
One of the best books on psychedelics I have read so far, then actually chemistry was a little beyond my knowledge, but the book is very informative
This book has it all, chemistry, cultural context, use, abuse, past, present and future. Is geared toward someone who has at least taken some o-chem, although non-science types could still get something out of it. The synthesis explanations can be a bit in depth, I have a degree in chemistry and a bit of that was way over my head. Book is also well refrenced, so should you ever get the urge to make some of these drugs you know where to go.
Very complete, encyclopedic review on the topic.
Even though this was billed as a "used" book, upon recieving it, it appears to be brand new to me!
I had to read this book for class and couldn't put it down. Perrine writes in such a way that can make any subject engrossing. Not only does he describe the effects of various substances, he also explains how they occur at the molecular level. Something most books about drugs don't do. He even discussed cultural elements, and some parts are quite humorous. It is not preachy or designed to scare and exaggerate like many books on the subject are. This book seems to be slightly biased in favor of some substances (most notably cannabis) but most of the book is about as objective as one can get, showing warts and all. You will certainly not want to run out and snort cocaine or shoot heroin or trip on acid after reading this book. But you may question the rationale as to why some substances are legal and others are not. The biggest downside is that it has not been updated since 1996, and much new information about mind-altering substances has been gained in the past 13 years. For example, we now know how DXM works on the brain as a dissociative (similar to PCP and ketamine--don't try this at home!), and back then Perrine (and others) assumed that the "trip" was just a placebo effect. He also did not mention any of the deliriants (anticholinergics), nor did he talk about Salvia. I would like to see a new edition sometime soon, preferably with better proofreading and organization, as well as more information added. A good complement to this book would "The Biochemical Basis of Neuropharmacology" by Cooper, Bloom, and Roth. Though that one is not quite as interesting as this book.If he were to update the book, I recommend that he break up the miscellaneous "Dissociatives and Cannabinoids" chapter into "Dissociatives and Deliriants," "Cannabis and Cannabinoids," and have an additional chapter for those that don't fit either. There are also many new substances to add as well.
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